Mesotherapy injections for carpal tunnel syndrome?

Mesotherapy for Carpal Tunnel Syndrome

Mesotherapy for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome (CTS) is the most common cause for hand pain, this recent study suggests that non invasive Mesotherapy injections, might play an integrative role, in CTS management. In our office, our integrative approach may include: bracing, limitation of aggravating factors, and activities, physiotherapy (ultrasound, IFC, and ICE.) recommendations for proper ergonomics. Furthermore, in severe forms of CTS, cortisone injections, and possibly referrals to hand surgeon might be indicated.

Intradermal Injections (mesotherapy) for the treatment of acute pain in carpal tunnel syndrome: a preliminary study.

The carpal tunnel syndrome (CTS) is the most common cause of severe hand pain. In this study we treated acute pain in CTS patients by means of local intradermal injections of anti-inflammatory drugs (mesotherapy).


In twenty-five patients (forty-five hands), CTS diagnosis was confirmed by clinical and neurophysiological examination prior to mesotherapy. A mixture containing lidocaine 10 mg, ketoprophen lysine-acetylsalycilate 80 mg, xantinol nicotinate 100 mg, cyanocobalamine 1,000 mcg plus injectable water was used. Sites of injection were three parallel lines above the transverse carpalligament and two v-shaped lines, one at the base of the thenar eminence, and the other at the base of the hypothenar eminence.


The day after the treatment, all but four patients reported a significant reduction in pain and paresthesias. After 12 months, 17 patients had a complete pain relief, eight patients reported recurrence of pain and sensory symptoms and four out of them underwent surgical treatment.


With the obvious limits of a small-size open-label study, our results suggest that mesotherapy can temporary relieve pain and paresthesias in most CTS patients and in some cases its effect seems to be long-lasting. Further controlled studies are needed to confirm our preliminary findings and to compare mesotherapy to conventional approaches for the treatment of CTS.



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